Table 3.
Binary logistic regression to predict worse therapeutic response in patients with atrial fibrillation using warfarin
| Variable | Group 1 vs group 4 | Group 2 vs group 4 | ||||
|---|---|---|---|---|---|---|
| p | OR | CI 95% | p | OR | CI 95% | |
| Age | 0.72 | 1.00 | (0.98–1.02) | 0.89 | 1.00 | (0.97–1.02) |
| Female sex | 0.66 | 0.82 | (0.35–1.92) | 0.01 | 3.57 | (1.35–9.09) |
| BMI | 0.94 | 1.03 | (0.41–2.58) | 0.95 | 1.02 | (0.37–2.8) |
| Heart failure | 0.03 | 2.45 | (1.08–5.55) | 0.16 | 1.96 | (0.75–5.08) |
| CYP2C9*3 (AA) | 0.47 | 0.58 | (0.13–2.53) | 0.08 | 0.18 | (0.02–1.28) |
| VKORC1 (GG) | 0.01 | 3.05 | (1.27–7.27) | 0.01 | 3.46 | (1.34–8.9) |
Notes: Group 1: TTR=0–45%; Group 2: TTR=46–60%; Group 4: TTR=81–100%. All statistically significant associations were highlighted in bold.
Abbreviation: BMI, body mass index.