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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: J Inherit Metab Dis. 2019 Mar 11;42(6):1128–1135. doi: 10.1002/jimd.12070

Fig 4. Liver-specific GS overexpression improved ammonia detoxification in Cps1-deficient mice.

Fig 4.

Plasma ammonia in Cps1-deficient (Cps1-def) mice injected with HDAd-GS (n = 9) or HDAd-AFP vector (n = 10) at baseline, 20 min and 60 min after i.p. injections of ammonium chloride (5 mmol/kg). #p≤ 0.05; *p< 0.05; **p< 0.01 (Two-way ANOVA; p= 0.0016). Control ammonia-treated wild-type mice are also included (n = 5). Data represent averages ± S.E.M. Abbreviations: Pi= post-injection.