Table 1.

Clinical information of the patients

Parameters	NO.	IL-22	P value	IL-22R	p value
Age (years)			0.824		0.742
<40	16	1.461 ± 0.73		1.627 ± 0.74
≥40	24	1.569 ± 1.07		2.123 ± 0.88
Tumor size (cm)			0.015		0.048
≥5	14	3.615 ± 0.89		2.842 ± 1.01
<5	26	1.899 ± 0.82		1.750 ± 0.97
Histological grade			0.738		0.685
Differentiation	19	2.311 ± 0.97		0.79
Poor differentiation	21	2.124 ± 1.12		1.868 ± 0.85
Invasion depth			0.139		0.417
Tis-T2	25	1.785 ± 0.88		1.679 ± 0.82
T3-T4	15	2.123 ± 0.89		1.821 ± 1.02
Lymph node metastasis			0.005**		0.004**
N0	6	1.168 ± 0.65		1.612 ± 0.65
N1-N3	34	3.080 ± 1.06		2.780 ± 0.98
Distant metastasis			0.003		0.038
M0	12	1.768 ± 0.38		1.263 ± 0.60
M1	28	2.866 ± 0.88		2.178 ± 1.21

^**P<0.01.