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. 2019 Jul 15;11(7):4516–4523.

Figure 2.

Figure 2

miR-223-3p promotes the proliferation and growth of colon cancer cells. (A and B) Negative control (NC) or miR-223-3p over-expressed RKO cells were subjected to qRT-PCR analysis of miR-223-3p expression (A) and CCK analysis of cell viability (B). *P < 0.05 and ***P < 0.001 compared with NC group. (C) Negative control (NC) or miR-223-3p silenced (Inhibitor) HCT 116 cells were subjected to CCK analysis of cell viability (C). *P < 0.05 and **P < 0.01 compared with NC group. (D and E) Colony formation analysis of NC or miR-223-3p over-expressed RKO cells. Representative images (D) and quantification (E) of colonies. **P < 0.01 compared with NC group. (F) Cells described in (A) were subjected to apoptosis measurement. **P < 0.01 compared with NC group. (G and H) Colony formation analysis of NC or miR-223-3p silenced HCT 116 cells. (G) Representative images (G) and quantification (H) of colonies. **P < 0.01 compared with NC group. (I) Cells described in (C) were subjected to apoptosis measurement. **P < 0.01 compared with NC group.