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. 2019 Jul 15;11(7):3945–3954.

Table 1.

Functional circRNA-miRNA-mRNA axis in breast cancer

circRNA Parental gene Sponged miRNA Targeted mRNA Specimen type Pairs of specimens Reference
Oncogenic
    hsa_circ_0000479 EPSTI1 miR-4753/6809 BCL11A Tissue 37 [37]
    hsa_circ_0001783 EBLN3 miR-200c-3p ZEB1/2, ETS1 Tissue 18 [35]
    hsa_circ_0001846 UBAP2 miR-661 MTA1 Tissue 78 [38]
    hsa_circ_0001982 RNF111 miR-143 N/A Tissue 29 [33]
    hsa_circ_0005230 DNM3OS miR-618 CBX8 Tissue 76 [43]
    hsa_circ_0005239 GFRA1 miR-34a GFRA1 Tissue 51 [20]
    hsa_circ_0005505 IRAK3 miR-3607 FOXC1 Tissue 35 [25]
    hsa_circ_0006528 PRELID2 miR-7-5p Raf1 Tissue 20 [45]
    hsa_circ_0007294 ANKS1B miR-148a-3p USF1 Tissue 20 [32]
miR-152-3p
    hsa_circ_0007534 DDX42 miR-593 MUC19 Tissue 40 [40]
    hsa_circ_0008039 PRKAR1B miR-432-5p E2F3 Tissue 38 [36]
    hsa_circ_0008717 ABCB10 miR-1271 N/A Tissue 32 [34]
    hsa_circ_0011946 SCMH1 N/A RFC3 Tissue 12 [39]
    hsa_circ_0052112 ZNF83 miR-125a-5p ZNF83 N/A N/A [23]
    hsa_circ_0058514 AGFG1 miR-195-5p CCNE1 Tissue 40 [44]
    hsa_circ_0072995 ARHGEF28 miR-30c-2-3p ARHGEF28 N/A N/A [24]
Anti-oncogenic
    N/A ITCH miR-214/miR-17 ITCH Tissue 91 [21]
    hsa_circ_0000911 IFNGR2 miR-449a Notch1 Tissue 35 [51]
    hsa_circ_0001098 BARD1 miR-3942 BARD1 Tissue 15 [22]
    hsa_circ_0007874 MTO1 N/A TRAF4/Eg5 N/A N/A [46]
    hsa_circ_0087378 NTRK2 miR-1260b SFRP1 Tissue 23 [52]