Table 4.
Variables | Patient N = 168 | Univariate Cox regression | Multivariate Cox regression | ||||
---|---|---|---|---|---|---|---|
|
|
||||||
B | HR (95% CI) | P value | B | HR (95% CI) | P value | ||
Age | 168 | 0.072 | 1.074 (0.662-1.744) | 0.771 | |||
< 65 | 98 | ||||||
≥ 65 | 70 | ||||||
Gender | 168 | -0.639 | 0.528 (0.228-1.222) | 0.136 | |||
Male | 141 | ||||||
Female | 27 | ||||||
BMI | 168 | -0.078 | 0.925 (0.57-1.5) | 0.752 | |||
< 25 | 98 | ||||||
≥ 25 | 70 | ||||||
Pathological T stage | 165 | 0.346 | 1.413 (0.855-2.335) | 0.177 | |||
T1+T2 | 72 | ||||||
T3+T4 | 93 | ||||||
Pathological N stage | 154 | 1.253 | 3.501 (1.881-6.517) | < 0.001 | 1.049 | 2.855 (1.035-7.872) | 0.043 |
N0 | 68 | ||||||
N1-N3 | 86 | ||||||
Pathological M stage | 148 | 1.209 | 3.351 (1.766-6.361) | < 0.001 | 0.295 | 1.342 (0.438-4.117) | 0.477 |
M0 | 133 | ||||||
M1 | 15 | ||||||
Pathological Stage | 163 | 1.083 | 2.954 (1.779-4.907) | < 0.001 | 0.858 | 2.358 (1.007-5.526) | 0.048 |
Stage I+II | 95 | ||||||
Stage III+IV | 68 | ||||||
Pathological Grade | 133 | 0.615 | 1.849 (1.081-3.164) | 0.025 | 0.014 | 0.986 (0.491-1.982) | 0.993 |
Grade 1+2 | 86 | ||||||
Grade 3 | 47 | ||||||
Residual tumor | 139 | 0.968 | 2.632 (1.331-5.205) | 0.005 | 0.722 | 2.059 (0.846-5.012) | 0.087 |
R0 | 125 | ||||||
R1+R2 | 14 | ||||||
Alcohol history | 167 | -0.319 | 0.727 (0.443-1.192) | 0.207 | |||
Yes | 48 | ||||||
No | 119 | ||||||
Smoke history | 148 | 0.092 | 1.096 (0.746-1.611) | 0.639 | |||
Yes | 96 | ||||||
No | 52 | ||||||
Barretts esophagus | 133 | 0.138 | 1.148 (0.643-2.048) | 0.641 | |||
Yes | 27 | ||||||
No | 106 | ||||||
Reflux history | 143 | 0.192 | 1.212 (0.699-2.101) | 0.494 | |||
Yes | 54 | ||||||
No | 89 |