Table 1.

RhoA immunoreactivity in melanoma cells and clinicopathological parameters

Clinicopathological parameters	RhoA IRS
	Low n = 46	High n = 88	p value
Age in years (18-87)a	(18-86)	(24-87)	0.075
mean: 61.6±14.8; median: 64.5	64.6±14.0; 68	60.0±15.0; 60.5
Genderb
Female	23	43	1.000
Male	23	45
Primary tumor locationc
Head/neck	5	6	0.470
Extremities	17	39
Hand/foot	2	1
Trunk	22	42
7th ed. AJCC stagec
I	12	36	0.052
II	15	34
III	11	13
IV	8	5
Primary tumor (pT)a
pT1	9	22	0.028
pT2	4	19
pT3	10	25
pT4	23	22
Regional lymph nodes status (pN)b
Metastases absent (pN-)	30	72	0.053
Metastases present (pN+)	16	16
Distant metastases (pM)b
Metastases absent (pM-)	38	83	0.061
Metastases present (pM+)	8	5
Sentinel lymph node biopsy statusb (60 patients)
No metastases	9	28	0.091
Metastases present	11	12
Recurrenceb
No	22	66	0.002
Yes	24	22

^a p value of Wilcoxon two sample test;

^b p value of Fisher’s exact test;

^c p value of chi² test.