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Anti-tumor effect of PRO-007 in FGFR2-modified GC cell lines. A. The viability of NCI-N87 cells transfected with FGFR2 cDNA was measured by the CTG assay after treatment with PRO-007 at 30 μg/ml. FGFR2 expression was confirmed by an immunoblotting assay. B. The viability of KATOIII cells transfected with FGFR2 shRNA was measured by the CTG assay after treatment with PRO-007 at 30 μg/ml. An immunoblotting assay showed decreased FGFR2 expression after transfection with FGFR2 shRNA.
