Figure 3.

B7-H3 increases the radioresistance of gastric cancer cells in vivo. Xenografts were established in nude mice to examine whether B7-H3 can increase the radioresistance of gastric cancer in vivo. Each group of mice was composed of six male nude mice. Tumor sizes were measured at 2-day intervals. A. There was no difference between the 7901 LV-NC group and the 7901 LV-B7-H3 group. However, gastric cancer cell growth was effectively suppressed in 7901 LV-B7-H3 cells exposed to 10 Gy X-ray irradiation (***P<0.001). B. Tumor xenografts from each group.