Table 2.
Effect of 2′-FL supplementation on the mesenteric lymph node immune cells proportion on day 16.
| Populations in MLN (%) | REF | 2′-FL |
|---|---|---|
| B cells (CD45RA+) | 30.53 ± 2.54 | 18.13 ± 2.19* |
| T cells (Th and Tc cells) | 62.01 ± 2.12 | 74.97 ± 2.03* |
| Th cells (CD4+ TCRαβ+ NK–) | 46.21 ± 1.32 | 55.56 ± 1.45* |
| CD62L+ | 23.46 ± 3.10 | 29.33 ± 1.80* |
| CD25+ | 2.15 ± 0.53 | 2.64 ± 0.08 |
| Tc cells (CD8+ TCRαβ+ NK- and TCRγδ+) | 15.80 ± 0.81 | 19.41 ± 0.62* |
| TCRαβ+ (CD8+ TCRαβ+ NK–) | 13.65 ± 0.81 | 16.91 ± 0.60* |
| TCRγδ+ | 2.15 ± 0.04 | 2.50 ± 0.05* |
| CD8+ | 1.52 ± 0.02 | 1.84 ± 0.06* |
| CD8– | 0.62 ± 0.05 | 0.66 ± 0.05 |
| NKT cells (TCRαβ+ NK+) | 2.99 ± 0.46 | 3.08 ± 0.22 |
| CD8+ | 1.72 ± 0.27 | 1.84 ± 0.11 |
| CD8– | 1.27 ± 0.19 | 1.24 ± 0.14 |
| NK cells (TCRαβ- NK+) | 3.43 ± 0.62 | 2.75 ± 0.16 |
| CD8+ | 0.47 ± 0.11 | 0.50 ± 0.05 |
| CD8– | 2.96 ± 0.51 | 2.25 ± 0.13 |
Results are expressed as mean ± S.E.M. (n = 4/group).
*
p < 0.05 compared to REF (by Student T-test).
Th, T-helper; Tc, T-cytotoxic; NK, Natural Killer; NKT, Natural Killer T; REF, reference; 2′-FL, 2′-fucosyllactose.