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. 2019 Aug 6;20:41. doi: 10.1186/s12868-019-0520-x

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effects of ISL on LPS-induced synaptic dysfunction. a–d Western blotting and histograms show the protein levels of synaptophysin, PSD-95 and BDNF in the hippocampus of each group. β-Actin was used as a loading control. Values are presented as mean ± SEM (n = 6). *p < 0.05 and **p < 0.01 vs. normal group, ^#p < 0.05 vs. LPS group. e Representative images show the immunoreactivities of PSD-95 in the CA1 subfield of the hippocampus by IF staining and BDNF in the CA3 subfield by IHC staining. Scale bars = 50 μm