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. 2019 Aug 6;14:27. doi: 10.1186/s13020-019-0249-6

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 10 — RSM down-regulates EGFR expression, and attenuates PI3K/AKT signaling in human HCC cells. Western blot analysis of EGFR, PI3K, AKT, and p-AKT in a MHCC97-H and b HepG2 cells. Data are presented as mean ± SD (n = 3), *P < 0.05, **P < 0.01, ***P < 0.001 versus the control group