Table 2.

Overview of Demographics, Imaging-Based Features, and Computational Fluid Dynamics Flow Inlet Conditions at Peak Inspiration of the Selected Subjects

	HF	HM	C1	C2	C3	C3a	C3b	C4	C4a	C4b
Demography
Sex	Female	Male	Female	Male	Female	Female	Female	Male	Male	Male
Age (years)	29	28	20	52	49	38	23	51	58	51
Weight (kg)	61.5	99	58.6	111.8	85.1	106.8	72.3	103	116.3	88.5
Asthma severity	N/A	N/A	Nonsevere	Nonsevere	Severe	Severe	Severe	Severe	Severe	Severe
Key imaging-based features of the selected subjects
J(Total)	2.0	2.4	3.3 (↑)	1.8 (↓)	1.9	2.2	2.2	1.4 (↓)	1.7 (↓)	1.7 (↓)
Dh* (sLLL)	0.35	0.38	0.37	0.24 (↓)	0.43	0.34	0.35	0.23 (↓)	0.30 (↓)	0.30 (↓)
CFD flow inlet conditions at PI
IC (L)	2.5	3.4	3.0	2.5	2.7	2.4	3.2	1.8	2.9	2.5
QPI (L/min)	50.2	66.7	60.2	50.5	53.3	48.5	63.4	35.8	57.1	50.5
Dh* (trachea)	1.17	0.99	0.88	0.94	1.23	1.07	1.11	0.97	0.85	1
Retrachea	4364	5364	6647	3905	3894	4047	5323	2742	4881	3715

Sex was considered when selecting subjects to eliminate sex bias. Arrows ↑ and ↓ in parentheses denote increase and decrease, respectively, of cluster-mean J(Total) and D_h^*(sLLL) in comparison with healthy subjects with a significance level of p < 0.001.

CFD, computational fluid dynamics; D_h^*, normalized hydraulic diameter; HF, healthy female; IC, inspiratory capacity; J, Jacobian determinant; PI, peak inspiration; Q_PI, maximum volumetric flow rate at peak inspiration; Re, Reynolds number.