Table 7.
Count of Whole Transcriptome Differentially Expressed Genes in Zf S1500+ Gene List Compared to Random Gene Sets of the Same Size for All Gene Expression Omnibus Datasets
Series | Comparison | Set | No. of genesa | No. of genes with RNA-Seq WTr datab | No. of RNA-Seq WTr DEGs in setc | Corrected percent of RNA-Seq DEGs in setd |
---|---|---|---|---|---|---|
GSE113676 | BPA Mid vs. Control | RNA-Seq WTr | 20,239 | 20,239 | 54 | |
Zf S1500+ | 3,055 | 2,983 | 8 | 14.6 | ||
Random1 | 3,055 | 2,924 | 12 | 22.3 | ||
Random2 | 3,055 | 2,904 | 6 | 11.2 | ||
Random3 | 3,055 | 2,925 | 7 | 13.0 | ||
BPA High vs. Control | RNA-Seq WTr | 20,239 | 20,239 | 148 | ||
Zf S1500+ | 3,055 | 2,983 | 34 | 22.6 | ||
Random1 | 3,055 | 2,924 | 26 | 17.6 | ||
Random2 | 3,055 | 2,904 | 16 | 10.9 | ||
Random3 | 3,055 | 2,925 | 21 | 14.2 | ||
GSE76564 | Regenerating Caudal Fin vs. Uninjured | RNA-Seq WTr | 17,371 | 17,371 | 371 | |
Zf S1500+ | 3,055 | 2,607 | 79 | 20.6 | ||
Random1 | 3,055 | 2,515 | 55 | 14.9 | ||
Random2 | 3,055 | 2,484 | 54 | 14.8 | ||
Random3 | 3,055 | 2,512 | 50 | 13.6 | ||
GSE75894 | Ablated Heart vs. Uninjured | RNA-Seq WTr | 17,371 | 17,371 | 545 | |
Zf S1500+ | 3,055 | 2,607 | 107 | 19.0 | ||
Random1 | 3,055 | 2,515 | 87 | 16.1 | ||
Random2 | 3,055 | 2,484 | 82 | 15.3 | ||
Random3 | 3,055 | 2,512 | 86 | 15.9 | ||
GSE100062 | Rods vs. Nonrod Retinas | RNA-Seq WTr | 17,629 | 17,629 | 1,018 | |
Zf S1500+ | 3,055 | 2,619 | 175 | 16.8 | ||
Random1 | 3,055 | 2,547 | 151 | 14.9 | ||
Random2 | 3,055 | 2,530 | 128 | 12.7 | ||
Random3 | 3,055 | 2,548 | 157 | 15.5 |
Number of genes in the set.
Number of genes in each set that were measured in the RNA-Seq dataset.
Number of DEGs from the WTr analysis of the RNA-Seq dataset that appear in each set.
Percent of DEGs from the WTr RNA-Seq dataset that appear in each set (c/b) where the count in c is corrected for the size in b with respect to the size of each subset. This is equivalent to multiplying by a correction factor of .
DEGs, differentially expressed genes.