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. 2019 Aug 6;38:342. doi: 10.1186/s13046-019-1342-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — CWP232291 blocks the growth of prostate cancer cells and primary cells derived from castration-resistant prostate cancer patients. a 22Rv1 and VCaP cells were exposed to CWP232291 (0–10 μM) and docetaxel (0–10 μM) for 72 h. Cell viability was determined using CellTiter Glo® (means ± SD, n = 3). b Docetaxel-resistant DU145 and parental DU145 cells were exposed to CWP232291 (0–10 μM) and docetaxel (0–10 μM) for 72 h. Cell viability was determined using CellTiter Glo® (means ± SD, n = 3). c Primary prostate cancer cells derived from patients with castration-resistant prostate cancer were exposed to CWP232291 (0–10 μM) for 72 h. Cell viability was determined using CellTiter Glo® (means ± SD, n = 3)