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. 2019 Aug 6;19:176. doi: 10.1186/s12903-019-0829-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Network of the interventional comparisons for the Bayesian network analysis. The size of the nodes is proportional to the number of subjects (sample size) randomized to receive the therapy. The width of the lines is proportional to the number of trials comparing each pair of treatments. aPDT, antimicrobial photodynamic therapy; Doxy, doxycycline; antibiotics (Doxy, metronidazole + amoxicillin); local, locally-delivered drugs (atorvastatin gel, chlorhexidine gel, simvastatin gel); laser (diode laser, aPDT); SDD, subantimicrobial dose doxycycline; SRP, scaling and root planing, NT, no treatment