Table 1:

CRP – Level

CRP Level	Rofecoxib PreOperative	Rofecoxib Postoperative	Total	Chi-Square Value
Less than 6 μg/ml	2 (10.5)	3 (15.8)	5 (13.2)	0.9037 (p=0.64)
6–24 µg/ml	13 (68.4)	14 (73.7)	27 (71.0)
48-96 µg/ml	4 (21.0)	2 (10.5)	6 (15.8)
Total	19 (100.0)	19 (100.0)	38 (100.0)

Chi-square value is insignificant.

Chi-square table value for degrees of freedom 2 @ 5% level is 5.99

Conclusion:- Giving rofecoxib to the patients 1 hour before and 5 minutes after the surgery does not have significant influence (change) in CRP level. That is, CRP level and timing of medication are independent of each other. There is no relationship.