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. 2019 Jul 31;10:1751. doi: 10.3389/fmicb.2019.01751

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Copyright © 2019 Li, Ye, Lv, Xu, Yang, Jiang, Wu, Shi, Fang, Bian, Wang, Wang, Xie, Lu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pretreatment with B. cereus reinforced the intestinal barrier function. (A) Representative images of H&E staining of the terminal ileum; ultrastructural and histological alterations in the ileum were assessed using ZO-1 immunofluorescence (IF) staining (×20). (B) Ileal inflammation was monitored based on the histology scores. Ileal mRNA expression of TLR-2 and TLR-3 was determined by quantitative PCR. All data are presented as the mean ± SEM. (NC group, n = 7; PC group, n = 6; B. cereus group, n = 7). ^aP < 0.05 and ^bP < 0.01 compared with the PC group, ^cP < 0.05 for the comparison of the B. cereus group with the NC group. NC, negative control; PC, positive control.