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. 2019 Jul 31;10:942. doi: 10.3389/fphys.2019.00942

TABLE 2.

Baseline hormonal levels according to reproductive function.

EUM (n = 16) FHA (n = 14) p-value
ACTH (μg/L) 18.7 ± 9.9 21.9 ± 7.8 0.35
Cortisol (nmol/L) 342 ± 119 375 ± 69 0.38
GH (μg/L) 0.71 ± 0.32 2.2 ± 3.7 0.15
IGF-1 (μg/L) 231 ± 51 219 ± 58 0.55
IGFBP-3 (μg/L) 5.4 ± 0.6 5.4 ± 1.6 0.95
Insulin (pmol/L) 107 ± 38 118 ± 68 0.60
Glucose (nmol/L) 4.8 ± 0.7 4.3 ± 0.9 0.60
Prolactin (μg/L) 231 ± 90 145 ± 28 <0.01
BDNF (μg/L) 113.7 ± 90.1 82.5 ± 64.3 0.30

Data shown as mean ± SD. ACTH, adrenocorticotropic hormone; BDNF, brain-derived neurotrophic factor; cortisol, GH, growth hormone; IGF-1, insulin-like growth factor 1; IGFBP3, insulin-like growth factor-binding protein 3 in athletes with EUM, eumenorrhea; FHA, functional hypothalamic amenorrhea.