TABLE 5.
Comparison of hormonal responses between Test1 and Test2, within and between reproductive function groups.
|
Difference in change from pre to post between Test1 and Test2 |
||||||
|
Within groups |
||||||
|
EUM (n = 16) |
FHA (n = 14) |
Between groups |
||||
| p-Value | p-Value | p-Value | ||||
| Prolactin (μg/L) | 108.4 ± 48.2 | 0.025 | 40.2 ± 49.1 | 0.413 | 68.2 ± 68.8 | 0.322 |
| ACTH (μg/L) | 1.33 ± 17.3 | 0.939 | −3.61 ± 7.7 | 0.839 | 4.94 ± 24.8 | 0.842 |
| Cortisol (nmol/L) | 46.1 ± 55.0 | 0.384 | 19.2 ± 54.0 | 0.722 | 27.0 ± 75.6 | 0.721 |
| GH (μg/L) | 12.0 ± 3.0 | 0.003 | 8.8 ± 2.9 | <0.001 | 3.2 ± 4.2 | 0.447 |
| IGF-1 (μg/L) | −4.8 ± 6.3 | 0.451 | 2.8 ± 6.1 | 0.650 | −7.5 ± 8.8 | 0.391 |
| IGFBP-3 (μg/L) | −0.3 ± 0.8 | 0.652 | 1.4 ± 0.8 | 0.058 | −1.8 ± 1.1 | 0.100 |
| Insulin (pmol/L) | 64.5 ± 20.5 | 0.002 | 76.2 ± 20.0 | <0.001 | −11.8 ± 28.6 | 0.681 |
| Prolactin:cortisol | 0.33 ± 0.21 | 0.111 | 0.06 ± 0.21 | 0.758 | 0.26 ± 0.29 | 0.370 |
| Cortisol:insulin | −0.003 ± 0.004 | 0.401 | −0.001 ± 0.004 | 0.734 | −0.002 ± 0.006 | 0.723 |
| GH:cortisol | 0.048 ± 0.014 | <0.001 | 0.030 ± 0.014 | 0.039 | 0.019 ± 0.204 | 0.358 |
| GH:insulin | 4.466 ± 0.262 | 0.026 | 3.391 ± 1.967 | 0.085 | 1.074 ± 2.811 | 0.702 |
| IGF-1:IGFBP-3 | 1.80 ± 1.70 | 0.289 | −2.16 ± 1.65 | 0.192 | 3.95 ± 2.37 | 0.095 |
| IGF:cortisol | −0.186 ± 0.135 | 0.170 | −0.065 ± 0.134 | 0.629 | −0.121 ± 0.190 | 0.527 |
| BDNF (μg/L) | 30.8 ± 32.8 | 0.348 | 54.6 ± 32.8 | 0.096 | −23.8 ± 46.4 | 0.608 |
Data shown as mean and standard error. EUM, Eumenorrheic athletes; athletes with FHA, functional hypothalamic amenorrhea; ACTH, adrenocorticotropic hormone; BDNF, brain derived neurotrophic factor; GH, growth hormone; IGF-1, insulin like growth factor 1; IGFBP-3, insulin like growth factor binding protein 3.