Table 1.

Synopsis of studied lichen planus patients.

P	Sex (m/f)	Age (y)	Clinical phenotype	Disease duration	Study drug	Treatment and observation period	Previous treatment
1	f	25	Disseminated cutaneous polygonal papules on the trunk and extremities, extensive erosions of the oral, and vaginal mucosa	3 months	Secukinumab 300 mg s.c. at weeks 0,1,2,3,4 followed by monthly treatment	12 weeks	none
2	f	56	Palmoplantar confluent polygonal papules and plaques, moderate erosions of the oral mucosa	6 months	Secukinumab 300 mg s.c. at weeks 0,1,2,3,4 followed by monthly treatment	12 weeks	Topical corticosteroids
3	f	58	Extensive erosions of the gingivae, tongue, buccal mucosa, and the palatine	7 years	Secukinumab 300 mg s.c. at weeks 0,1,2,3,4 followed by monthly treatment	48 weeks (ongoing)	Ciclosporin, systemic and topical corticosteroids, acitretin, intravenous immunoglobulins
4	f	72	Extensive erosions of the oral mucosa, pronounced painful, and recalcitrant ulcerations of the tongue and gingivae	6 years	Ustekinumab 45 mg s.c. at weeks 0 and 4 and every 3 months thereafter	48 weeks (ongoing)	Ciclosporin, systemic and topical corticosteroids, acitretin, azathioprine
5	f	72	Recalcitrant ulcerations of the tongue	5 years	Guselkumab 100 mg s.c. at weeks 0 and 4 and every 2 months thereafter	30 weeks (ongoing)	Systemic and topical corticosteroids