TABLE 3.
Results of Cognitive Appraisal at the Time of [F-18]FDDNP-PET Scan
| No. | Type of appraisal | Results |
|---|---|---|
| 1. | Gross cognitive functioning | Mini-Mental State Examination: 25 out of 30. |
| 2. | Intellectual functioning | Average range—Wechsler Test of Adult Reading (estimate of premorbid general intellectual functioning; 30th percentile, estimated FIQ = 92). |
| 3. | Attention/Concentration | Impaired range—WAIS-III Digit Span (ninth percentile); able to recite 7 digits forward and 3 digits backward. |
| 4. | Psychomotor/Information processing speed | Low average to impaired range—WAIS-III Digit Symbol Coding (copying symbols to match a set; 16th percentile). |
| Stroop B (rapid word reading; fifth percentile). | ||
| Stroop A (rapid color reading; second percentile). | ||
| Tails A (drawing lines to connect a series of numbers; <first percentile). | ||
| 5. | Language | Average to impaired range—CFL (phonic fluency; 33rd percentile). |
| Animals (semantic fluency; ninth percentile). | ||
| Boston Naming (confrontation naming; <first percentile). | ||
| 6. | Visual-spatial functioning | Average range—WAIS-III Block Design (50th percentile). |
| Rey-O Copy, 32/36 (46th percentile). | ||
| 7. | Executive functioning | Average to impaired range—WAIS-III Similarities (verbal abstract reasoning; 63rd percentile). |
| WCST (flexibility and concept formation: completed 6/6 categories (16th percentile with several errors; 32nd percentile) | ||
| Animals (semantic fluency; ninth percentile). | ||
| Trails B (set-shifting; fifth percentile). | ||
| Stroop C (inhibiting automatic responses; first percentile). | ||
| 8. | Memory | Immediate memory: impaired range (WMS-III Verbal Pairs I: 25th percentile; WMS-III Logical Memory I: first percentile; Buschke Total: <first percentile). |
| Delayed memory: impaired range (WMS-III Verbal Pairs II: ninth percentile; WMS-III Logical Memory II: fifth percentile; Buschke Delay: <first percentile). | ||
| 9. | Hamilton Depression Rating (17-item) | 8 |
| 10. | Hamilton Anxiety Scale | 13 |
Comprehensive psychopathological cognitive assessment of the patient at the time of the [F-18]FDDNP-PET scan for the in vivo detection of neuropathological substrates in the brain. Our subject was diagnosed with mild cognitive impairment with deficits in multiple cognitive domains, eg, memory, attention, information processing speed, language, and executive functioning.