Table 1.

Calculated concentrations of metabolites in the NAD⁺ metabolome in multiple matrices: HEK-293 cells, human red blood cells, non-human primate skeletal muscle and human cerebrospinal fluid.

	Cells (μM)	RBC (μM)	Muscle (nmol/g)	CSF (μM)
NAD	104.65 ± 13.35	25.40 ± 3.88	226.8 ± 4.3	0.072 ± 0.008
NADH	9.30 ± 2.07	3.18 ± 0.22	45.2 ± 3.1	BQ
ADPR	3.17 ± 0.14	3.11 ± 0.36	29.2 ± 11.8	BQ
NADP	27.01 ± 7.42	5.57 ± 0.59	3.76 ± 0.71	ND
NADPH	23.25 ± 3.73	5.50 ± 0.67	BQ	ND
NAAD	BQ	BQ	2.39 ± 1.00	ND
NMN	1.13 ± 0.32	0.81 ± 0.10	0.42 ± 0.05	0.081 ± 0.001
NAMN	0.61 ± 0.15	0.52 ± 0.12	BQ	ND
NR	BQ	0.37 ± 0.06	BQ	BQ
NAM	10.03 ± 1.32	14.39 ± 0.72	68.1 ± 8.9	ND
AcCoA	23.32 ± 4.03	1.31 ± 0.06	1.25 ± 0.47	BQ