Table I:
Hemodynamic parameter | Baseline | 30 min post MI | Eight weeks after MI | ||
---|---|---|---|---|---|
Resting 5 μg/kg/min | Dobutamine 10 μg/kg/min | Dobutamine | |||
Systolic ABP (mmHg) | 89.0 ± 9.6 | 81.1 ± 9.3a | 88.1 ± 9.9 | 97.8 ± 12.9b | 99.6 ± 14.9b |
Systolic PAP (mmHg) | 29.2 ± 4.6 | 31.2 ± 7.8 | 35.1 ± 2.3a | 35.8 ± 3.0 | 37.2 ± 2.0b |
Maximum dP/dt (mmHg/s) | 909 ± 244 | 988 ± 464 | 840 ± 158d | 1529 ± 377a,b,c | 2284 ± 436a,b,c,d |
Minimum dP/dt (mmHg/s) | −1151 ± 257 | −986 ± 473 | −963 ± 159a | −1251 ± 221 | −1646 ± 495a,b,c |
PCWP (mmHg) | 13.7 ± 3.3 | 17.1 ± 6.7a | 20.3 ± 3.8a | 20.3 ± 3.5a | 18.3 ± 3.7a |
CVP (mmHg) | 11.4 ± 4.4 | 11.6 ± 3.9 | 17.3 ± 3.5a,b | 16.7 ± 2.6a,b | 14.0 ± 3.2 |
Cardiac output (1/min) | 3.5 ± 1.0 | 3.1 ± 0.6 | 4.5 ± 1.6b | 7.1 ± 2.4a,b,c | 6.7 ± 1.9a,b,c |
All values are mean ± SD.
ABP: Arterial blood pressure; CVP: Central venous pressure; MI: Myocardial infarction; PAP: Pulmonary artery pressure; PCWP: Pulmonary capillary wedge pressure.
p <0.05 versus baseline;
p <0.05 versus 30 min after MI;
p <0.05 versus resting condition;
p <0.05 versus dobutamine 5 μg/kg/min.