Table II:
Measurement | Baseline | 30 min post MI | Eight weeks after MI | ||
---|---|---|---|---|---|
Resting | Dobutamine 5 μg/kg/min | Dobutamine 10 μg/kg/min | |||
MR grade | 0.7 ± 0.5 | 0.9 ± 0.7 | 2.0 ± 1.2a,b | 2.6 ± 1.2a,b | 2.6 ± 1.3a,b |
LVEF (%) | 40.3 ± 6.6 | 31.4 ± 5.8a | 25.8 ± 7.7a | 29.8 ± 7.5a | 32.6 ± 10.7a |
LVEDV (ml) | 51.9 ± 8.7 | 57.9 ± 8.5 | 102.0 ± 24.1a,b | 84.4 ± 24.0a,b,c | 70.6 ± 19.1a,b,c,d |
LVESV (ml) | 31.2 ±6.8 | 39.8 ± 7.3a | 75.8 ± 20.3a,b | 59.6 ± 20.8a,b,c | 47.7 ± 16.1a,c |
All values are mean ± SD.
LVEDV: Left ventricular end-diastolic volume; LVEF: Left ventricular ejection fraction; LVESV: Left ventricular end-systolic volume; MI: Myocardial infarction.
p <0.05 versus baseline;
p <0.05 versus 30 min after MI;
p <0.05 versus resting condition,
p <0.05 versus dobutamine 5 μg/kg/min.