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. Author manuscript; available in PMC: 2019 Aug 7.
Published in final edited form as: Nat Genet. 2017 May 29;49(7):993–1004. doi: 10.1038/ng.3875

Figure 2.

Figure 2

Manhattan plot of the results from the GWAS discovery plus replication meta-analysis comprising 13,620 XFS cases and 109,837 controls. Genetic markers are plotted according to chromosomal location on the horizontal axis and statistical significance on the vertical axis. SNP markers at seven independent loci surpass genome-wide significance (defined as P<5×10−8). They are LOXL1, CACNA1A, POMP, TMEM136, AGPAT1, SEMA6A and RBMS3.