Figure 4.

In vivo targeting and biodistribution of dual‐targeting N₃‐TINPs. A) In vivo imaging analysis of mice after administered with different nanoparticles. B) The major organs and tumors of mice with the indicated treatment were harvested for ex vivo imaging at 48 h postinjection. C) The ICG content of each organ was quantified by fluorescence. D) The generation of BCN groups on tumor tissues were recorded by confocal microscopy. E,F) Evaluating the enrichment of N₃‐TINPs in tumor tissues. The tumor tissue sections of mice administered different treatments were stained with anti‐CD3‐FITC and DBCO‐Flour 488. Scale bar: 50 µm. Statistical P‐values: (**) P < 0.01.