Table 3.
Free catecholamine levels in the cecal lumen of gnotobiotic micea.
GF mice | Gnotobiotic mice | |||
---|---|---|---|---|
Clostridia | Cc | EX-GF | ||
Norepinephrine (ng/g) | 2.6 ± 0.3 | 27 ± 3*** | 82 ± 5*** | 18 ± 1*** |
Dopamine (ng/g) | 16.3 ± 0.7 | 114 ± 9*** | 132 ± 16*** | 120 ± 16*** |
Cecal luminal contents collected from either germ-free (GF) (n = 6), Clostridia (n = 6), Clostridium coccoides (Cc, n = 6), or whole SPF microbiota (EX-GF, n = 6)-reconstituted mice were processed for free catecholamine measurements (26).
P < 0.001 indicates significantly higher than the corresponding GF value.