Table 4.
Luminal 5-HT concentration in the gastrointestinal tract of GF mice after recolonization with SPF fecal microbiotaa.
| 5-HT (ng/g) | ||||
|---|---|---|---|---|
| Basal | Day 3 | Day 7 | Day 21 | |
| Ileum | 139 ± 106 | 218 ± 107 | 330 ± 183* | 128 ± 116 |
| Cecum | 80 ± 20 | 535 ± 189*** | 547 ± 56*** | 381 ± 127*** |
| Colon | 230 ± 212 | 724 ± 198*** | 862 ± 230*** | 743 ± 241*** |
a
Luminal contents of germ-free (GF) mice were subjected to 5-HT measurements before (basal) and at 3, 7, or 21 days after exposure to specific pathogen-free (SPF) fecal microbiota (23).
*
P <0.05 and
***
P <0.001 compared to the corresponding basal value.