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. 2019 May 22;6(15):1900605. doi: 10.1002/advs.201900605

Figure 7.

Figure 7

Cell membrane‐based detoxification for ameliorating inflammation. A) Pore‐forming toxins (PFTs) can be arrested and locked by red blood cell membrane‐coated nanosponges. B) Skin lesions on mice occurred 3 d following injection of α‐toxin or α‐toxin/nanosponges (n = 6 for each group). C) Survival rates of mice over 15 d after a tail vein injection of α‐toxin or α‐toxin/nanosponges (80 mg kg−1 nanosponges were injected 2 min after the toxin injection, n = 9). Reproduced with permission.[qv: 105b] Copyright 2013, Nature Publishing Group. D) Schematic representation of T‐cell membrane‐coated nanoparticles (TNPs) for attenuating HIV infectivity. CD4+ T cell membrane with CD4 receptor and CCR5 or CXCR4 coreceptors were used for viral targeting. TNPs neutralization against bystander T‐cell killing induced E) by gp120IIB or F) with gp120BaL. Data shown as the mean ± SD, *p < 0.05, **p < 0.01, and ***p < 0.001. Reproduced with permission.106 Copyright 2018, Wiley.