Figure 10.

Cell membrane‐based nanotherapeutics targeting gastrointestinal diseases. A) Ex vivo imaging of colons from mice treated with liposomes (LIPO), leukosomes (LEUKO), or specialized leukosomes (SLKs). B) The relative fluorescence intensities between the outside and inside of the vessels (n = 10 vessels per image). C) Histopathological scores of colon tissues of healthy mice and DSS mice treated with different nanoparticles (n = 6). *p < 0.1; **p < 0.01; ***p < 0.001; ****p < 0.0001. Reproduced with permission.[qv: 30d] Copyright 2017, Royal Society of Chemistry. D) Schematic illustration showing the fabrication of MRINs by coating nanoparticle containing MSC‐conditioned media. E) Survival rates of animal after different treatment (n = 10 per group). Reproduced with permission.111 Copyright 2018, American Chemical Society.