Table 1.
Sample | Sex | Age | Tissue sample | Site | size | MI | KIT/PDGFRA mutation | TKI therapy | Miettinen score | Platform |
---|---|---|---|---|---|---|---|---|---|---|
GIST002 | F | 85 | Primary | Stomach | 8 | <5 | KIT exon 11 V560D | No | Low | Microarray |
GIST004 | M | 79 | Primary | Stomach | 5 | 7 | KIT exon 9 ins 502–503 | No | Intermediate | Microarray |
GIST005 | M | 68 | Primary | Stomach | 7 | 4 | PDGFRA exon 12 del/ins SPDGHE566–571RIQ | No | Low | Microarray |
GIST008 | M | 62 | Primary | Stomach | 2 | 4 | KIT exon 11 V559D | No | Low | Microarray |
GIST009 | M | 54 | Primary | Stomach | 3 | <5 | KIT exon 11 ins TQLPYDHKWEFP 574–585 | No | Low | Microarray |
GIST011 | M | 77 | Metastasis | Stomach | 20 | >10 | KIT exon 11 del WK557–558 | Imatinib | High | RNA-seq |
GIST012 | F | 66 | Primary | Stomach | 4 | <5 | PDGFRA exon 14 K646E | No | Low | Microarray |
GIST013 | M | 46 | Primary | Ileum | 7 | <5 | KIT exon 11 V559D | No | Low | Microarray |
GIST015 | F | 64 | Primary | Stomach | 5.5 | <5 | PDGFRA exon 18 del DIMH842-845 | No | Low | Microarray |
GIST016 | F | 62 | Primary | Stomach | 3.7 | NA | KIT exon 11 L576P | No | NA | Microarray |
GIST018 | M | NA | NA | NA | >5 | NA | KIT exon 11 V559G | No | NA | Microarray |
GIST020 | M | 38 | Metastasis | Ileum | NA | NA | KIT exon 11 del MYEQW552–557 | NA | NA | Microarray |
GIST022 | F | 76 | NA | Stomach | NA | NA | PDGFRA exon18 D842V | NA | NA | Microarray |
GIST025 | M | 84 | NA | NA | NA | NA | KIT exon 11 del/ins WKV557–559F | NA | NA | Microarray |
GIST026 | M | 49 | Metastasis | Stomach | NA | NA | PDGFRA exon 12 V561D | NA | NA | Microarray |
GIST121 | M | 71 | Primary | Stomach | 5.5 | 4 | KIT exon 11 V559D | No | Low | Microarray |
GIST124 | M | 73 | Metastasis | Stomach | 17 | >10 | KIT exon 11 ins 1765–1766 | Imatinib and sunitinib | High | RNA-seq |
GIST125 | F | 48 | Primary | Stomach | 6 | 5 | KIT exon 11 W557R | No | Low | Microarray |
GIST129 | M | 59 | Primary | Stomach | 5 | 5 | KIT exon 11 del/ins YEVQWKV553–559L | No | Intermediate | Microarray |
GIST130 | F | 79 | Primary | Stomach | 7 | >10 | KIT exon 9 ins 502-503 | No | High | Microarray |
GIST131 | M | 68 | Metastasis | Ileum | 6 | 3 | KIT exon 11 del VYIDPTQLPY569-578 | Imatinib and sunitinib | Intermediate | RNA-seq |
GIST135 | F | 61 | Primary | Stomach | 3.5 | 6 | KIT exon 11 del WKVVE557-561 | No | Intermediate | Microarray |
GIST136 | M | 76 | Primary | Stomach | 4.5 | 6 | PDGFRA exon 18 D842V | No | Intermediate | RNA-seq |
GIST138 | F | 75 | Primary | Stomach | 7 | 8 | PDGFRA exon 18 D842V | No | High | RNA-seq |
GIST140 | F | 45 | Primary | Stomach | 2 | 2 | PDGFRA exon 18 D842V | No | Low | RNA-seq |
GIST142 | M | 68 | Primary | Stomach | 3 | 5 | PDGFRA exon 18 D842V | No | Low | RNA-seq |
GIST150 | F | 58 | Primary | Stomach | 7 | 68 | KIT exon 11 del PMYE551-554 | No | High | RNA-seq |
GIST165 | M | 51 | Primary | Stomach | 12 | <2 | PDGFRA exon 18 D842V | No | Intermediate | RNA-seq |
GIST174 | M | 61 | Primary | Stomach | 6 | 14 | KIT exon 11 L576P | Imatinib | High | RNA-seq |
GIST178 | F | 70 | Primary | Stomach | 10 | >5 | KIT exon 11 V559D | No | High | RNA-seq |
GIST188 | F | 62 | Primary | Duodenum | 4 | >5 | KIT exon 11 del NGNNYVYIDPTQL564-576 | Imatinib and sunitinib | Intermediate | RNA-seq |