Table 1.
Patient characteristics and their association with death after discharge from hospitalization with melioidosis
| Patient feature | Total, n = 228 | Alive at the end of the study period, n = 176 | Died during follow-up, n = 52 | P-value * | Odds ratio (95% CI) | P-value† |
|---|---|---|---|---|---|---|
| Demographic | ||||||
| Age ≥ 60 years‡ | 68 (30%) | 52 (30%) | 16 (31%) | 0.87 | 1.06 (0.54–2.08) | 0.87 |
| Male gender | 167 (73%) | 129 (73%) | 38 (73%) | 0.98 | 0.99 (0.49–1.99) | 0.98 |
| Indigenous | 120 (53%) | 88 (50%) | 32 (62%) | 0.14 | 1.60 (0.85–3.01) | 0.15 |
| Disease risk factor | ||||||
| Chronic lung disease | 31 (14%) | 16 (9%) | 15 (29%) | < 0.0001 | 4.05 (1.84–8.93) | 0.001 |
| Chronic kidney disease | 34 (15%) | 20 (11%) | 14 (27%) | 0.006 | 2.87 (1.33-6.20) | 0.007 |
| Diabetes mellitus | 123 (54%) | 91 (52%) | 32 (62%) | 0.21 | 1.49 (0.79–2.81) | 0.21 |
| Hazardous alcohol use | 92 (40%) | 68 (39%) | 24 (46%) | 0.33 | 1.36 (0.73-2.54) | 0.33 |
| Immunosuppression | 35 (15%) | 24 (14%) | 11 (21%) | 0.19 | 1.70 (0.77–3.75) | 0.19 |
| Malignancy | 20 (9%) | 13 (7%) | 7 (13%) | 0.17 | 1.95 (0.73–5.18) | 0.18 |
| Inhospital course | ||||||
| Bacteremia | 165 (72%) | 127 (72%) | 38 (73%) | 0.90 | 1.04 (0.52–2.10) | 0.90 |
| ICU admission | 55 (24%) | 42 (24%) | 13 (25%) | 0.87 | 1.06 (0.52–2.18) | 0.87 |
| Septic shock | 46 (22%) | 34 (21%) | 12 (26%) | 0.43 | 1.36 (0.64–2.90) | 0.43 |
ICU = intensive care unit.
* Calculated using chi-square or Fisher’s exact test where appropriate.
† P-value for odds ratio calculated using logistic regression.
‡ At the time of initial admission to hospital with melioidosis.