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. 2019 Jul 26;55(3):645–656. doi: 10.3892/ijo.2019.4849

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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RAC2 expression may be a diagnostic biomarker in patients with ccRCC. (A) RAC2 effectively discriminated between ccRCC and paired normal tissues (AUC 0.9095; P<0.0001). Receiver operating characteristic curve subanalysis was performed with respect to the following subgroups of patients with ccRCC: (B) G grade, (C) T stage, (D) lymph node metastasis, (E) distant metastases, (F) Tumor-Node-Metastasis stage, (G) overal survival and (H) disease free survive. RAC2, Rac family small GTPase 2; ccRCC, clear cell renal cell carcinoma; AUC, area under the curve; OS, overall survival; DFS, disease-free survival.