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. 2019 Jul 26;55(3):645–656. doi: 10.3892/ijo.2019.4849

Figure 7.

Figure 7

RAC2 promotes the proliferation, invasion and migration of RCC cell lines in vitro. (A and B) Reverse transcription-qauntitative PCR and western blotting assays of RAC2 knockdown in ACHN and 786-O cells; β-actin was used as a loading control. (C and D) Cell counting kit-8 assays detected the effects of RAC2 knockdown on the proliferation of ACHN and 786-O cells. (E-H) Representative images of migration and invasion assays performed using ACHN and 786-O cells (magnification, ×100). Data are presented as the mean ± standard deviation from three independent experiments. ****P<0.0001; ***P<0.001; **P<0.01 and *P<0.05 vs. si-NC. RAC2, Rac family small GTPase 2; ccRCC, clear cell renal cell carcinoma; NC, negative control; si-RNA, small interfering RNA; OD value, optical density value.