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. 2019 Aug 7;5(8):eaau3460. doi: 10.1126/sciadv.aau3460

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Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

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Fig. 5 — (A) ROI analyses of the right CST ROI in the midbrain show significantly reduced FA in individuals diagnosed with a concussion compared to matched controls. (B) There is a negative correlation between peripheral tau and structural integrity of the midbrain in concussed individuals, indicating that higher levels of peripheral tau are associated with greater reductions in structural integrity of the midbrain CSTs.