Table 2.
Differences between dyads who were and were not prenatally exposed to SRIs in the current follow-up studies.
| Online Questionnaire Study | SRI Exposed (n=75) | Unexposed (n=62) | Between-Group Differences |
|---|---|---|---|
| Child age in years, Mean (SD) | 7.4 (1.2) | 7.2 (1.3) | t(135) = −1.0 |
| Child gender, n (% out of 100) | 37 (49.3) Male | 39 (62.9) | Χ2(1,137) = 2.5 |
| Child race, n (%) | 57 (76.0) Caucasian | 51 (82.3) | Χ2(1,127) = 0.8 |
| Child IQ, Mean (SD) | 105.9 (15.1) | 104.9 (13.3) | t(135) = −0.4 |
| Child Apgar scores Mean (SD) | 8.8(0.5) | 8.9(0.5) | t(135)=0.7 |
| Children in residence, Mean (SD) | 1.9 (0.3) | 2.0 (0.2) | t(135) = 0.7 |
| No. of delivery complications, Mean (SD) | 0.9 (0.9) | 0.6 (1.0) | t(135) = −1.7 |
| EGA at delivery, Mean (SD) | 38.8 weeks (1.4) | 38.9 (1.6) | t(135) = 0.4 |
| Maternal Marital status, n (%) | 59 (78.7) Married | 53 (85.5) | Χ2(1, 137) = 0.8 |
| Maternal age in years, Mean (SD) | 41.8 (4.7) | 40.2 (4.7) | t(135) = −1.9 |
| Prenatal depression AUC, Mean (SD) | 465.1(342.6) | 340.9(254.9) | t(135)=−2.3* |
| In-Depth Laboratory Study | SRI Exposed (n=27) | Unexposed (n=17) | Between-Group Differences |
| Child age in years, Mean (SD) | 5.6 (1.0) | 5.0 (0.9) | t(42) = −1.8 |
| Child gender, n (% out of 100) | 10 (37.0) Male | 9 (52.9) | Χ2(1,44) = 1.1 |
| Child race, n (%) | 22 (81.5) Caucasian | 12 (70.6) | Χ2(1,44) = 0.4 |
| Child IQ, Mean (SD) | 108.5 (14.5) | 107.8 (11.6) | t(42) = −0.2 |
| Child Apgar scores Mean (SD) | 8.9 (0.3) | 8.94 (0.3) | t(42)=0.5 |
| Children in residence, Mean (SD) | 2.2 (1.0) | 2.0 (0.8) | t(42) = −0.7 |
| No. of delivery complications, Mean (SD) | 0.9 (0.8) | 1.1 (1.1) | t(42) = 0.7 |
| EGA at delivery, Mean (SD) | 38.9 weeks (1.1) | 39.4 (1.7) | t(42) = 1.0 |
| Maternal Marital status, n (%) | 24 (88.9) Married | 14 (82.4) | Χ2(1,44) = 0.4 |
| Maternal age in years, Mean (SD) | 40.1 (4.2) | 38.7 (5.4) | t(42) = −1.5 |
| Paternal age in years, Mean (SD) | 41.5 (5.7) | 40.2 (6.1) | t(42) = −0.8 |
| Prenatal depression AUC, Mean (SD) | 432.4 (290.3) | 330.7(239.8) | t(42)=−1.2 |
Note:
*
p<0.05 difference between referent and comparison groups.
EGA = estimated gestational age. Child, maternal, and paternal age represents the age at the indicated follow-up. Prenatal depression AUC = depression scores across pregnancy calculated as the area under the curve from the Beck Depression Inventory assessed multiple times throughout pregnancy.