Table 1. DICE coefficient/COME results of the deformed liver tumor contour for the patient study.

Patients	No. of projects	Prior w/o deformation (mm)	2D-3D deformation (mm)	2D-3D deformation with MM (mm)	Bio-CBCT (mm)	MM-Bio-CBCT (mm)
P1	5	0.52/11.6 (DICE/COME)	0.61/9.8	0.84/3.1	0.86/2.5	0.91/0.3
	10		0.63/9.3	0.85/3.0	0.88/1.7	0.92/0.7
	20		0.80/4.6	0.86/2.5	0.88/1.7	0.91/0.9
P2	5	0.49/8.3	0.59/7.0	0.73/4.3	0.76/3.2	0.81/2.3
	10		0.60/6.7	0.74/4.2	0.80/2.6	0.82/2.2
	20		0.70/4.6	0.75/4.0	0.82/2.2	0.83/2.1
P3	5	0.39/7.1	0.39/7.1	0.59/4.4	0.55/4.9	0.74/2.2
	10		0.39/7.1	0.59/4.4	0.56/4.6	0.74/2.2
	20		0.39/7.1	0.60/4.3	0.65/3.7	0.74/2.1

Varying numbers of projections (5, 10 and 20) were used for CBCT estimation. MM, motion modeling. COME, center-of-mass-error; CBCT, cone-beam computed tomography.