Table 3.
Odds ratio estimates for latent BMI trajectory classes and pancreatic cancer among cases diagnosed in 2011–2013 and controls recruited in 2011, from Ontario, Canada
| Trajectory classes | Cases | Controls | Model 1 | Model 2 | Model 3 | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| n = 310 | % | n = 1,258 | % | ORa | 95% CI | ORb | 95% CI | ORc | 95% CI | |
| Class 1: stable-normal weight | 117 | 38 | 493 | 39 | 1.00 | 1.00 | 1.00 | |||
| Class 2: progressively overweight | 128 | 41 | 534 | 43 | 1.07 | 0.81, 1.43 | 1.17 | 0.86, 1.60 | 1.15 | 0.84, 1.58 |
| Class 3: persistent overweight | 349 | 16 | 149 | 12 | 1.55 | 1.04, 1.32 | 1.72 | 1.12, 2.64 | 1.63 | 1.05, 2.53 |
| Class 4: progressive obesity | 14 | 5 | 51 | 4 | 1.35 | 0.72, 2.54 | 1.70 | 0.88, 3.30 | 1.51 | 0.77, 2.99 |
| Class 5: persistent obesity | 2 | 0.7 | 31 | 3 | 0.36 | 0.08, 1.53 | 0.24 | 0.03, 1.79 | 0.22 | 0.03, 1.70 |
aAdjusted for age group and sex
bAdjusted for age group, sex, race, alcohol consumption, smoking, vegetable consumption, fruit consumption, red meat consumption, current moderate physical activity, current vigorous physical activity, family history of pancreatic cancer
cAdjusted for all variables in Model 2 plus pancreatitis, diabetes