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. 2019 Jul 10;9(7):190099. doi: 10.1098/rsob.190099

Figure 2.

Figure 2.

Structures of a number of AMPK activators. They have been classified according to their mechanisms of activation of AMPK (see §§3.1–3.3). (a) Pro-drugs that are converted inside cells to AMP analogues. (b) Compounds that bind in the allosteric drug and metabolite (ADaM) site. (c) Compounds that activate indirectly by inhibiting mitochondrial ATP synthesis.