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. 2019 Aug 7;9:11460. doi: 10.1038/s41598-019-48019-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The ribosome nascent chain tunnel environment Left: The 70S S. aureus (SA_WT) ribosome where the large subunit is shown in light grey and the small subunit is shown in dark grey (PDBID 5TCU). The A-site, P-site and E-site docked tRNA molecules (from PDBID 5JTE) are shown in blue, green and magenta, respectively. The surface of a nascent chain within the tunnel is shown in yellow. Erythromycin surface is shown in red, uL4, uL22, uL23 and uL24 are shown in brown, orange, teal and khaki, respectively. Right: zoom into the ery binding site at the upper tunnel.