Table 2.
Model designation | Parameter | pH of the release medium | |||
---|---|---|---|---|---|
4.4 | 5.4 | 6.4 | 7.4 | ||
Zero-order | R2 Observed | −1.1654 | −0.5274 | −1.0925 | −0.7970 |
R2 Adjusted | −1.1655 | −0.5274 | −1.0925 | −0.7970 | |
First-order | R2 Observed | 0.8271 | 0.7938 | 0.3866 | −0.1928 |
R2 Adjusted | 0.8271 | 0.7938 | 0.3866 | −0.1928 | |
Higuchi | R2 Observed | 0.7364 | 0.8673 | 0.7510 | 0.8137 |
R2 Adjusted | 0.7364 | −0.5274 | 0.7510 | 0.8137 | |
Korsmeyer-Peppas | R2 Observed | 0.9968 | 0.9949 | 0.9950 | 0.9940 |
R2 Adjusted | 0.9964 | 0.9943 | 0.9944 | 0.9932 | |
n | 0.3119 | 0.3518 | 0.3157 | 0.3331 | |
Hixson-Crowell | R2 Observed | 0.6991 | 0.6439 | 0.0846 | −0.3756 |
R2 Adjusted | 0.6991 | 0.6439 | 0.0846 | −0.3756 | |
Baker-Lonsdale | R2 Observed | 0.9812 | 0.9921 | 0.9308 | 0.8844 |
R2 Adjusted | 0.9812 | 0.9922 | 0.9308 | 0.8844 |
R:2 coefficient of determination. n: diffusion exponent.