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. 2019 Aug 7;9:11462. doi: 10.1038/s41598-019-46653-3

Table 3.

Tissue Doppler Results in 128 children with CKD, stratified by CKD stage. Tissue Doppler Velocities (Z-Scores, Mean ± SD).

All CKD 2-3b CKD 4-5 Dialysis
E’
Mitral anular −0.24 ± 1.07* −0.14 ± 1.20 −0.24 ± 0.99 −0.62 ± 0.94
Septal −0.69 ± 1.02*** −0.60 ± 1.10 −0.77 ± 1.00 −0.58 ± 0.88
Combined −0.45 ± 0.94*** −0.37 ± 1.05 −0.48 ± 0.90 −0.60 ± 0.77
A’
Mitral anular 0.21 ± 1.11* −0.02 ± 0.97B;C 0.21 ± 1.11A 1.01 ± 1.35A
Septal 0.22 ± 0.96*** 0.04 ± 1.02 0.33 ± 0.95 0.29 ± 0.74
Combined 0.23 ± 0.95* 0.01 ± 0.90B 0.30 ± 0.96A 0.65 ± 0.89
S’
Mitral anular −0.11 ± 1.03 −0.17 ± 1.05 −0.10 ± 1.01 0.09 ± 1.10
Septal −0.38 ± 0.93*** −0.39 ± 0.81 −0.43 ± 1.03 −0.09 ± 0.81
Combined −0.24 ± 0.85* −0.28 ± 0.84 −0.26 ± 0.86 0.002 ± 0.90
E’/A’ (diastolic function)
Mitral anular −0.08 ± 0.34* 0.03 ± 0.35C −0.09 ± 0.31C −0.40 ± 0.18B
Septal −0.20 ± 0.40*** −0.10 ± 0.43 −0.26 ± 0.36 −0.19 ± 0.40
Combined −0.14 ± 0.3*** −0.03 ± 0.34B,C −0.18 ± 0.28A −0.29 ± 0.18 A
E/E’ (LV compliance)
Mitral anular 0.34 ± 0.98** 0.18 ± 0.83 0.35 ± 1.01 0.82 ± 1.18
Septal 0.81 ± 1.21*** 0.63 ± 1.10 0.95 ± 1.22 0.85 ± 1.54
Combined 0.57 ± 1.00*** 0.40 ± 0.89 0.64 ± 1.01 0.83 ± 1.31

*p < 0.05;**p < 0.001;***p < 0.0001 compared to reference population.

A: different from CKD 2-3b; B: different from CKD 4–5; C: different from Dialysis (all p < 0.05).