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. Author manuscript; available in PMC: 2019 Aug 8.
Published in final edited form as: Immunohorizons. 2019 Jul 2;3(7):274–281. doi: 10.4049/immunohorizons.1900042

FIGURE 3. Epigenome-wide differential methylation in RUL macrophages.

FIGURE 3.

Comparative analysis of DNA methylation in upper versus lower lobe macrophages in healthy subjects identified 95 differentially methylated CpGs (FDR p < 0.05). CpGs hypermethylated in RUL (green), and hypomethylated CpGs (blue) are plotted as log2-fold increase or decrease in methylation M value (x-axis) versus log10 FDR-adjusted p value (y-axis). Statistically significant CpGs associated with specific genes are labeled, and unlabeled points represent CpGs associated with no known gene at that location.