Table 1.
Summary of studies included in the systematic review
| Author | Study design | Sample size (n) | Measurement | 1st degree AVB prevalence | Outcome (major arrhythmic events) | Event [+]/event [−] | Mean PR intervalc (event [+]/event [−]) | Odds ratioc;95% CI; P‐value 1st degree AVB event [+]/event [−] | Follow‐up months |
|---|---|---|---|---|---|---|---|---|---|
| Corcia 2017 | Cohort | 95 | ECG | 16 (17%) | VT/VF/appropriate ICD shocks/ICD implantation | 24/71 | 181.6 ± 53.3/161.3 ± 30.5b | N/A | 33.8 |
| Corcia‐2 2017 | Cohort | 128 | ECG | 39 (30.5%) | VT/VF/appropriate ICD shocks | 40/88 | 181.35 ± 44.72/154.73 ± 29.64 | 3.42 (1.53‐7.64); 0.003 | 21 |
| Juntilla 2008 | Case‐Control | 200 | ECG | N/A | Syncope/VT/VF/appropriate ICD shocks | 66/134 | 181 ± 34/178 ± 39b | N/A | None |
| Maury 2013 | Cohort | 325 | ECG | 113 (35%) | Syncope/VT/VF/appropriate ICD shocks | 113/185 | N/A | 2.61 (1.16‐5.85); 0.02 | 48 |
| Migliore 2018 | Cohort | 272 | ECG | 45 (16.5%) | VT/VF/appropriate ICD shocks | 17/255 | N/A | 5.24 (1.90‐14.44); 0.001 | 85 |
| Morita 2018 | Cohort | 471 | ECG | 69 (14.64%)a | Syncope/VT/VF/appropriate ICD shocks | 145/326 | 180 ± 29/174 ± 26 | 1.34 (0.78‐2.28); 0.29a, b | 91 |
| Ohkubo 2011 | Cohort | 35 | ECG | N/A | Syncope/VT/VF | 10/25 | 178.9 ± 20/168 ± 19.6b | N/A | 84.5 |
Abbreviations: AVB, atrio‐ventricular block; ECG, 12‐lead electrocardiogram; N/A, not applicable/available; VF, ventricular fibrillation; VT, ventricular tachycardia; ICD, implantable cardioverter defibrillator.
a
Morita et al did not specify the type of atrioventricular block; it might not be first‐degree.
b
Not statistically significant (P > 0.05).
c
Calculated using RevMan 5.3.