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. 2019 Aug 7;17:256. doi: 10.1186/s12967-019-2006-0

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — The effects of saline, R-7050 (TNFα receptor antagonist), DETC (superoxide dismutase inhibitor), PEG-SOD (superoxide scavenger) and Apo (NADPH oxidase inhibitor) pretreatment in the PVN on the AAR response to TNFα in the PVN. TNFα (1 ng) was administered 10 min after the pretreatment. The values are mean ± SD. For each group, n = 6–7; *p < 0.05 versus Saline + Saline; ^#p < 0.05 versus Saline + TNFα (1 ng); ^&p < 0.05 versus Control