Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 7;17:256. doi: 10.1186/s12967-019-2006-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 5 — The effects of R-7050 pretreatment on the NADPH oxiase activity (f), ROS level (e) and the in situ ROS content (a–d) responses to TNFα in the PVN. In situ ROS was determined with a specific fluorogenic probe by the DHE method (n = 3 for each group). The NADPH oxiase activity was detected by the enhanced lucigenin chemiluminescence method and the ROS level were measured by the lucigenin-derived chemiluminescence method (n = 6 for each group). The values are mean ± SD; *p < 0.05 versus Control + Saline + Saline; ^#p < 0.05 versus OH + Saline + Saline; ^&p < 0.05 versus OH + Saline + TNFα. PVN paraventricular nucleus, 3V the third ventricle