Table 2.
Changes in echocardiography parameters during follow-up grouped by HOMA-IR tertiles
| HOMA-IR tertiles | Low | Intermediate | High | P-value |
|---|---|---|---|---|
| LVEDD, mm | ||||
| B | 50.09 (4.35) | 50.77 (5.00) | 51.60 (5.23) | < 0.001 |
| F | 50.60 (4.99) | 51.68 (5.49) | 53.04 (5.33) | |
| Δ | 0.52 (2.47) | 0.91 (3.08) | 1.44 (3.96) | |
| LVESD, mm | ||||
| B | 34.04 (5.09) | 34.93 (5.35) | 35.55 (5.40) | < 0.001 |
| F | 33.89 (5.43) | 34.93 (6.14) | 36.60 (6.37) | |
| Δ | − 0.15 (3.351) | 0.00 (2.94) | 1.05 (4.11) | |
| LVEDVI, mL/m2 | ||||
| B | 70.17 (12.65) | 69.61 (13.88) | 70.28 (16.67) | < 0.001 |
| F | 72.09 (14.60) | 72.66 (16.56) | 75.00 (17.84) | |
| Δ | 1.91 (7.96) | 3.06 (10.63) | 4.66 (13.20) | |
| LVESVI, mL/m2 | ||||
| B | 29.11 (9.97) | 29.46 (10.55) | 30.32 (11.55) | < 0.001 |
| F | 28.65 (11.00) | 29.86 (12.95) | 32.28 (14.21) | |
| Δ | − 0.46 (6.68) | 0.40 (6.38) | 1.96 (9.13) | |
| LVMI, g/m2 | ||||
| B | 93.55 (17.15) | 96.39 (21.13) | 96.21 (21.67) | 0.130 |
| F | 94.47 (18.35) | 95.32 (16.69) | 93.66 (17.95) | |
| Δ | 0.91 (15.84) | − 1.07 (17.75) | − 2.73 (15.24) | |
| IVST, mm | ||||
| B | 9.27 (1.04) | 9.55 (1.15) | 9.60 (1.10) | 0.003 |
| F | 9.14 (1.11) | 9.36 (1.04) | 9.01 (1.16) | |
| Δ | − 0.13 (1.21) | − 0.19 (1.22) | − 0.59 (1.48) | |
| LVPWT, mm | ||||
| B | 8.92 (0.92) | 9.20 (1.07) | 9.19 (0.97) | 0.006 |
| F | 8.93 (0.91) | 8.92 (0.85) | 8.83 (0.75) | |
| Δ | 0.01 (1.03) | − 0.28 (1.09) | − 0.37 (1.25) | |
| RWT | ||||
| B | 0.36 (0.04) | 0.37 (0.05) | 0.37 (0.05) | 0.001 |
| F | 0.36 (0.04) | 0.36 (0.05) | 0.34 (0.05) | |
| Δ | − 0.01 (0.05) | − 0.01 (0.04) | − 0.03 (0.06) | |
| LVEF, % | ||||
| B | 59.04 (8.03) | 58.20 (7.85) | 57.76 (7.35) | 0.089 |
| F | 60.89 (7.63) | 59.99 (7.53) | 58.22 (8.36) | |
| Δ | 1.85 (6.76) | 1.79 (5.40) | 0.47 (6.80) | |
Values are given as mean (standard deviation)
B baseline, Δ changes in corresponding parameters, F follow-up, IVST interventricular septal thickness, LVEDD left ventricular end-diastolic diameter, LVEDVI left ventricular end-diastolic volume indexed to body surface area, LVEF left ventricular ejection fraction, LVESD left ventricular end-systolic diameter, LVESVI left ventricular end-systolic volume indexed to body surface area, LVMI left ventricular mass indexed to body surface area, LVPWT left ventricular posterior wall thickness, RWT relative wall thickness