Table 4.
Multivariate linear regression analysis for ∆LVEDD after STEMI
| Covariates | Model 1 | Model 2 | ||||
|---|---|---|---|---|---|---|
| Coefficient (95% CI) | Sβ | P-value | Coefficient (95% CI) | Sβ | P-value | |
| Male gender | − 0.009 (− 1.044 to 1.025) | − 0.001 | 0.986 | 0.028 (− 1.004 to 1.061) | 0.003 | 0.957 |
| Age | − 0.190 (− 0.453 to 0.073) | − 0.066 | 0.157 | − 0.125 (− 0.385 to 0.135) | − 0.043 | 0.345 |
| Smoking | 0.446 (− 0.138 to 1.030) | 0.067 | 0.134 | 0.366 (− 0.218 to 0.949) | 0.055 | 0.219 |
| Hypertension | 0.351 (− 0.220 to 0.923) | 0.052 | 0.228 | 0.339 (− 0.226 to 0.905) | 0.050 | 0.239 |
| CKD | 0.886 (− 0.220 to 1.991) | 0.066 | 0.116 | 0.855 (− 0.230 to 1.939) | 0.063 | 0.122 |
| Lymphocytes | − 1.028 (− 1.563 to − 0.492) | − 0.166 | < 0.001 | − 1.049 (− 1.581 to − 0.517) | − 0.169 | < 0.001 |
| HDL cholesterol | − 3.118 (− 4.722 to − 1.515) | − 0.163 | < 0.001 | − 3.265 (− 4.878 to − 1.651) | − 0.170 | < 0.001 |
| TIMI flow ≤ 2 | 1.215 (− 0.460 to 2.890) | 0.059 | 0.155 | 1.489 (− 0.182 to 3.161) | 0.072 | 0.081 |
| Log cTnI | 0.109 (0.007 to 0.211) | 0.092 | 0.036 | 0.114 (0.012 to 0.216) | 0.096 | 0.029 |
| Basal LVEDD | − 0.293 (− 0.359 to − 0.227) | − 0.435 | < 0.001 | − 0.317 (− 0.384 to − 0.251) | − 0.471 | < 0.001 |
| Basal LVEF | − 0.145 (− 0.187 to − 0.103) | − 0.344 | < 0.001 | − 0.145 (− 0.186 to − 0.104) | − 0.343 | < 0.001 |
| HOMA-IR | < 0.001* | 0.088* | ||||
| Tertile 2 vs. 1 | 1.196 (0.541 to 1.851) | 0.170 | < 0.001 | − 0.361 (− 1.360 to 0.638) | − 0.051 | 0.478 |
| Tertile 3 vs. 1 | 1.926 (1.237 to 2.614) | 0.272 | < 0.001 | 1.224 (0.095 to 2.353) | 0.173 | 0.034 |
| IGT | – | – | – | − 1.337 (− 2.311 to − 0.363) | − 0.185 | 0.007 |
| IGT × HOMA-IR | – | – | – | 0.001† | ||
| βint (tertile 2 vs. 1) | – | – | – | 2.453 (1.162 to 3.744) | 0.260 | < 0.001 |
| βint (tertile 3 vs. 1) | – | – | – | 1.925 (0.561 to 3.288) | 0.197 | 0.006 |
| BMI | – | – | – | 0.760 (− 0.249 to 1.769) | 0.113 | 0.140 |
| BMI × HOMA-IR | – | – | – | 0.212† | ||
| βint (tertile 2 vs. 1) | – | – | – | 0.775 (− 0.566 to 2.117) | 0.088 | 0.257 |
| βint (tertile 3 vs. 1) | – | – | – | − 0.405 (− 1.796 to 0.985) | − 0.049 | 0.567 |
BMI body mass index, cTnI cardiac troponin I, CKD chronic kidney disease, HOMA-IR homeostasis model assessment-estimated insulin resistance, IGT impaired glucose tolerance, LVEDD left ventricular end-diastolic diameter, LVEF left ventricular ejection fraction, Sβ standardized coefficient, βint regression coefficient (interaction)
*P for trend; †P for interaction