Table 3.
Prediction of Fluid Responsiveness based on the ROC Curves of Various Indices
| AUC (95%CI) | P-value | Cut-off value,% | Sensitivity (95% CI) | Specificity (95% CI) | Grey zone (%) | Patients in the grey zone number (%) | |
|---|---|---|---|---|---|---|---|
| PPV6 | 0.69 (0.52–0.83) | 0.036 | > 6 | 54 (33–74) | 79 (49–95) | 3.2 to 7.8 | 22 (58) |
| SVV6 | 0.56 (0.39–0.72) | 0.563 | – | – | – | ||
| PPV8 | 0.85 (0.70–0.95) | < 0.0001 | > 7 | 79 (58–93) | 79 (49–95) | 6.2 to 8.6 | 10 (26) |
| SVV8 | 0.77 (0.61–0.89) | 0.0003 | > 5 | 67 (45–84) | 79 (49–95) | 2.7 to 6.3 | 21 (55) |
| ΔPPV6–8 | 0.95 (0.83–0.99) | < 0.0001 | > 1 | 92 (73–99) | 86 (57–98) | 1 to 1.3 | 9 (24) |
| ΔSVV6–8 | 0.76 (0.60–0.89) | 0.0006 | > 2 | 46 (26–67) | 100 (77–100) | −1.5 to 1.4 | 21 (55) |
| %ΔPPV6–8 | 0.87 (0.72–0.96) | < 0.0001 | > 25 | 83 (63–95) | 79 (49–95) | 20.5 to 46 | 12 (32) |
| %ΔSVV6–8 | 0.71 (0.55–0.85) | 0.02 | > 16.7 | 67 (45–85) | 79 (49–95) | −32 to 95 | 27 (71) |
ROC Receiver operating characteristic, AUC Area under the curve, CI Confidence interval, PPV6 Pulse pressure variation during tidal volume at 6 ml/kg predicted body weight (PBW), SVV6 Stroke volume variation during tidal volume at 6 ml/kg PBW, PPV8 Pulse pressure variation during tidal volume at 8 ml/kg PBW, SVV8 Stroke volume variation during tidal volume at 8 ml/kg PBW, ΔPPV6–8 Change in value of pulse pressure variation after tidal volume challenge, ΔSVV6–8 Change in value of stroke volume variation after tidal volume challenge, %ΔPPV6–8 Percentage change in value of pulse pressure variation after tidal volume challenge, %ΔSVV6–8 Percentage change in value of stroke volume variation after tidal volume challenge